Agata Piotrowska-Mastalerz is a graduate of the State Higher School of Drama in Cracow. Until 2001 she was associated with the Stefan Jaracz Theatre in Łódź. Her more important roles include: Susanna in The Marriage of Figaro by P. Beaumarchais (dir. Anna Augustynowicz), Gretchen in Mein Kampf by G. Tabori (dir. Tomasz Zygadło), Doris Levin in God by W. Allen (dir. Tomasz Zygadło), Bride in The Curse by St. Wyspiański (dir. Waldemar Zawodziński), Areusa in Celestine by F. de Rojas (dir. Waldemar Zawodziński), Cecilia in A Crime with Premeditation by W. Gombrowicz (dir. Zbigniew Brzoza), Masha in The Three Sisters by A. Chekhov (dir. Barbara Sass), Secretary in The Procession by W. Schwab (dir. Bogdan Hussakowski).
Since 1999 she has been working at the Studio Theatre in Warsaw. Last season she played Milena in The Family Situations by Biljana Srbljanović, directed by Piotr Łazarkiewicz.